On my cars that have it - yes I do use it all the time. As said already in this thread, it provides dry air so therefore reduces condensation on colder days. Warmer days speak for themselves.
With my 240, I use the "analogue air con" and use the vents on the A pillars as I find them very effective at providing cooler air on the move. When standing, I have to use those funny little handle things on the inside of the door to lower the windows
